CHARACTERISTICS OF COVID-19 RELATED STROKE: A SINGLE-CENTER PROSPECTIVE STUDY

Characteristics of COVID-19 Related Stroke: A Single-center Prospective Study

Characteristics of COVID-19 Related Stroke: A Single-center Prospective Study

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Objective:Coronavirus disease-2019 (COVID-19) seems more related to stroke than other respiratory viruses.Acute stroke has become increasingly conspicuous during a typical COVID-19 infection.In the present study, we aim to evaluate stroke characteristics in the context of COVID-19 infection.Method:We conducted a single-center prospective study and evaluated Body Brushes characteristics of stroke patients who had concomitant definite COVID-19 (dCOV) (n=24), suspected COVID-19 (sCOV) (n=31), and no COVID-19 (CG) (n=19).

Then we classified all participants into two groups according to the modified Rankin scale (mRS) scores (0-2 indicating good outcome, 3-6 indicating poor outcome).A logistic regression analysis and a receiver operating characteristic area under the curve were performed to evaluate the variables, which predict a poor prognosis.Results:Just over half of the patients in the dCOV were admitted with stroke symptoms and diagnosed with COVID-19 at admission, and nearly half of the patients initially had a COVID-19 diagnosis.They had developed stroke after a gap of 4-21 days.

Ischemic stroke was the most common stroke Girls Accessories subtype in dCOV.The dCOV had higher mRS indicating poor outcomes.Patients with poor outcomes had higher levels of D-dimer, neutrophil-to-lymphocyte ratio (NLR), procalcitonin, and aspartate aminotransferase.NLR reliably predicts poor outcome, overall with an accuracy of 86%.

Conclusion:COVID-19 related stroke is associated with high inflammatory biomarkers, poor outcome, and high mortality.NLR is a potential, cost-effective, and easy-to-use marker for poor prognosis in COVID-19 related stroke.

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